Application of BMP-2 for bone graft in Dentistry

Resumo

The global increase life expectancy and the resulting
tooth loss has required searching for new rehabilitation alternatives
in Dentistry. Biomaterials can be defined as any material that acts
replacing a lost bone defect and its function. In Dentistry, many
studies have aimed to improve bone regeneration through the use
of BMPs for bone replacement. Objective: To review the literature
on the use and clinical viability of human morphogenetic protein
for the jaws reconstruction. Material and methods: The following
databases were searched: Pubmed, Bireme, Lilacs, and Scielo and
30 articles published between 1965 and 2013 were found using
the following descriptors: “dental implants”, “maxillary sinus”, and
“biocompatible materials”. Results: Several studies demonstrate the
biological advantages of rhBMP-2 on bone regeneration of the jaws.
In recent years, morphogenetic protein has presented a large clinical
use. Conclusion: Despite being a high-cost biomaterial, rhBMP-2 is
a viable and very effective alternative for reconstruction of defects
of the face.