Eosinophilic ulcer of the lateral tongue: case report

Resumo

Introduction: Eosinophilic ulcer of the oral mucosa (EUOM) is a
lesion manifesting as ulcer with elevated margins. The lesion is selflimiting and develops rapidly usually disappearing after several weeks.
The exact pathogenetic mechanisms implicated in its development
are poorly understood, however, the possibility that trauma may play
a role has been often postulated. Case report: A 63 year-old male
patient had presented whit a chief complaint of painful ulcerated
nodule on the tongue. Oral examination revealed a firm, raised
and indurated erythematous nodule with a central ulcer that had
a yellow fibrinous base. Clinical diagnosis hypothesis was either
traumatic ulcer or oral squamous cell carcinoma. Histopathologic
analysis revealed an ulcerated lesion with a dense mixed infiltrate of
eosinophils, variably sized lymphocytes and epithelioid cells extending
into submucosa. These cells exhibited pleomorphism, voluminous
cytoplasm and nucleus with prominent nucleolus and were identified
by immunohistochemical method as CD68+ cells. The histological
diagnosis was EUOM. At 1-year follow-up there was no recurrence.
Conclusion: Our case provides useful information on clinical and
pathological features, diagnosis, treatment, and prognosis of EUOM,
as suggesting the possible etiology of this uncommon lesion because
it is poorly described in the literature.