Preemptive analgesia – evaluation of the effect of paracetamol and dipyrone after tooth whitening

Sandro Dias Rocha Mendes Carneiro, Ana Julieta Almeida Rodrigues, Sarah Valentim Diniz, Danilo Lopes Ferreira Lima, Fernando André Campos Viana


To evaluate the effect of preemptive analgesia of paracetamol and dipyrone in vital teeth professionally whitened in office. Material and methods: This was a pilot study of a blinded, paired sample, randomized clinical trial. Twenty volunteers requiring dental whitening, received, after the randomization, one
of the formulations under study, one hour before the procedure: paracetamol 500 mg or dipyrone 500 mg as preemptive medications. Data collection was conducted by using two instruments: a record of research evaluation and visual analog scale (VAS), in which the patient was asked to score a value to the pain experienced before, during, 1 hour and 6 hours after the whitening procedure. Results: Most participants were female (75 %), of the age group between 18
and 27 years (75%). During the measurement of pain at pre- and trans-operative periods, VAS showed no statistically significant differences. At the post-operative period, immediately after, one and 6 hours after, clinically and statistically significant differences were observed, thus evidencing the superiority of treatment with Dipyrone 500 mg over the treatment with paracetamol 500 mg (p = 0.042, p = 0.003 and 0.0017, respectively). Conclusion: Dipyrone 500 mg exhibited higher effectiveness than Paracetamol 500 mg in the study population, as a technique of preemptive analgesia in tooth
whitening procedure.



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